Infectious Disease
The goal of the Infectious Disease Translational Research Laboratory is to develop rapid diagnostic methods for the determination of synergy or antagonism between two or more antimicrobial agents against multidrug-resistant bacteria and fungi. We developed an Etest® methodology that is very promising in this regard. Our research also involves evaluation of rapid diagnostic testing for direct-from-blood organisms and resistance genes.
Transplant
Working to (1) Increase recipient access to orthotopic liver transplantation (OLT) through identification and targeting critical mediators of tissue damage caused by ischemia/reperfusion (I/R) injury. (2) Identify (a) diagnostic biomarkers in hepatocellular carcinoma (HCC) for patients at high risk for metastasis and (b) HCC-mutation profiles which can predict therapeutic susceptibility and limit risk of recurrence after OLT.