linked in pixel Ochsner Journal Spotlight: Multiple Left Atrial Undifferentiated Pleomorphic Sarcomas

Release Date: March 20, 2025

Ochsner Journal Static Front

Undifferentiated pleomorphic sarcoma is an exceedingly rare and aggressive primary cardiac tumor, and left atrial undifferentiated pleomorphic sarcoma is an even rarer subtype, occurring in 1% of cases. Prognosis is poor, with survival after diagnosis often <1 year. In this case, the patient presented with the nonspecific symptoms of angina and dyspnea on exertion. Cardiac MRI showed multiple masses in the left atrium that pathology identified as high-grade undifferentiated pleomorphic sarcoma. Following surgical resection and chemotherapy, the patient survived >2 years.

images of undifferentiated pleomorphic sarcoma

Read the full text of this case report in the Winter issue of Ochsner Journal: https://www.ochsnerjournal.org/content/24/4/279