Search Clinical Trials

ABI-009 (Nab-rapamycin) + FOLFOX & Bevacizumab as First-line Therapy for Advanced or Metastatic CRC

A phase 1/2 multi-center investigation of ABI-009 (nab-rapamycin) in combination with mFOLFOX6 and Bevacizumab as first-line therapy in patients with advanced or metastatic colorectal cancer.…

ABI-009 in Metastatic, Unresectable, Low or Intermediate Grade Neuroendocrine Tumors

The purpose of this study is to determine whether ABI-009 will make advanced, malignant neuroendocrine tumor(s) of the lung, gastrointestinal tract and/or pancreas that cannot…

Study of LOXO-292 in Advanced Solid Tumors, RET Fusion+ Solid Tumors, and Medullary Thyroid Cancer

This is a Phase 1/2, open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics (PK) and preliminary anti-tumor activity of LOXO-292 administered orally to…

Phase 1/2 Study of LOXO-195 in Patients with Previously Treated NTRK Fusion Cancers

This is a Phase 1/2, multi-center, open-label study designed to evaluate the safety and efficacy of LOXO-195 when administered orally to patients age ≥ 1…

CT Perfusion in Predicting Outcomes in Ovarian Cancer Receiving Bevacizumab

This phase II trial studies how well computed tomography perfusion imaging works in predicting outcomes in patients with ovarian, fallopian tube, or primary peritoneal cancer…

Pacritinib for PMF, PPV-MF, or PET-MF Previously Treated with Ruxolitinib

The study is designed to support a Pacritinib dosage selection decision. 3 dosages will be evaluated, with patients randomized 1:1:1 to Pacritinib 100 mg QD,…

Olaparib, Cediranib, and Wee1 Inhibitor for Recurrent, Refractory, or Metastatic Endometrial Cancer

This randomized phase II trial studies how well Olaparib, Cediranib maleate, and Wee1 Inhibitor, AZD1775, work in treating patients with endometrial cancer that has come…

KEYNOTE-224: Pembrolizumab as Monotherapy for Advanced Hepatocellular Carcinoma

This is an efficacy and safety study of Pembrolizumab (KEYTRUDA®) as monotherapy in participants with HCC in 2 cohorts: participants with advanced HCC and with…

Palbociclib and Letrozole or Fulvestrant for ER Positive, HER2 Negative Metastatic Breast Cancer

This phase II trial studies the side effects and how well Palbociclib and Letrozole or Fulvestrant works in treating patients aged 70 years and older…

Gemcitabine and Cisplatin in Treating Participants with Invasive Bladder Urothelial Cancer

This phase II trial studies how well Gemcitabine hydrochloride and Cisplatin work in treating participants with invasive bladder urothelial cancer. Click here to download the…