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VICTORIA

VICTORIA will test the hypothesis that vericiguat is superior to placebo in increasing the time to first occurrence of the composite of cardiovascular (CV) death…

HALO

The Amulet™ device will be evaluated for safety and efficacy by demonstrating its performance is non-inferior to the commercially available WATCHMAN® left atrial appendage closure…

Amulet™ (AMPLATZER™ Amulet™ LAA Occluder Trial (Amulet IDE))

The Amulet™ device will be evaluated for safety and efficacy by demonstrating its performance is non-inferior to the commercially available WATCHMAN® left atrial appendage closure…

CTD-PAH SWITCH (Crossover Study from Macitentan or Bosentan Over to Ambrisentan (Letairis))

This study is being conducted to learn more about the safety & effects of switching from bosentan (Tracleer) or macitentan (Opsumit) to ambrisentan (Letairis) over…

SPHERE (Uptravi® (SelixiPag): The Users Drug Registry)

This registry is being conducted in order to further outline the clinical characteristics, outcomes and dosing/titration regiments of patients treated with Uptravi in routine clinical…

WISE LE Study (Evaluation of WIRION™ EPS in Lower Extremities Arteries)

The purpose of this study is to demonstrate the safety & performance of the WIRION™ EPS in subjects undergoing lower extremity atherectomy for the treatment…

Reveal LINQ™ Heart Failure (LINQ HF)

The primary objective of this registry is to characterize Reveal LINQ™ derived data from patients with heart failure by assessing the relationship between changes in…

RAPID (Registry of Angiovac Procedures in Detail Outcomes Database)

The primary objective of this registry is to determine the procedure related mortality associated with the use of the AngioVac device, which is an FDA…

RADIANCE-HTN (A Study of the ReCor Medical Paradise System in Clinical Hypertension)

This clinical trials is designed to demonstrate efficacy and document the safety of the Paradise Renal Denervation System in two distinct populations of hypertensive subjects.

Portico™ (Re-sheathable transcatheter Aortic Valve System US IDE Trial)

The PORTICO clinical trial is a prospective, multi-center, randomized, controlled clinical study, designed to evaluate the safety and effectiveness of the SJM Portico Transcatheter Heart…