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The purpose of this study is to evaluate Orbital Atherectomy compared to conventional balloon angioplasty technique prior to stent implantation for treatment of severely calcified…

EARLY TAVR (Evaluation of Transcatheter Aortic Valve Replacement Compared to Surveillance for Patien

The purpose of this study is to evaluate the TAVR compared to surveillance for patients with asymptomatic severe aortic stenosis.

Brady MRI PAS (SJM Brady MRI Post Approval Study)

The purpose of this study is to evaluate the long-term safety of the FDA approved St. Jude Medical Tendril MRI lead implanted with a SJM…

PARADISE-MI (Prospective ARNI vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Fail

The purpose of this study is to evaluate the efficacy and safety of LCZ696 titrated to a target dose of 200 mg twice daily, compared…

MOMENTUM 3 (Momentum 3 CAP Continued Access Protocol)

The objective of the study is to continue to evaluate safety and clinical performance of the HM3 LVAS for the treatment of advanced, refractory, left…

ELITE (Eliminate Thombroembolism: Improving Anticoagulation in Non-valvular Atrial Fibrillation Pati

This study is a 2 year research project to assess warfarin management issues faced by atrial fibrillation patients in ambulatory settings.

LIFE Study/HFN-LIFE

This study’s primary objective is to determine whether, in patients with symptomatic, advanced heart failure due to left ventricular systolic dysfunction, treatment with LCZ696 for…

invested

INVESTED will test the hypothesis that high dose trivalent influenza vaccine will reduce cardiopulmonary events to a greater extent than standard dose quadrivalent influenza vaccine…

PREVENT II

PREVENT II is a prospective study of subjects receiving the HM II LVAD as per the current FDA approved indications for use that will investigate…

VICTORIA

VICTORIA will test the hypothesis that vericiguat is superior to placebo in increasing the time to first occurrence of the composite of cardiovascular (CV) death…