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LIFE Study/HFN-LIFE

This study’s primary objective is to determine whether, in patients with symptomatic, advanced heart failure due to left ventricular systolic dysfunction, treatment with LCZ696 for…

invested

INVESTED will test the hypothesis that high dose trivalent influenza vaccine will reduce cardiopulmonary events to a greater extent than standard dose quadrivalent influenza vaccine…

PREVENT II

PREVENT II is a prospective study of subjects receiving the HM II LVAD as per the current FDA approved indications for use that will investigate…

VICTORIA

VICTORIA will test the hypothesis that vericiguat is superior to placebo in increasing the time to first occurrence of the composite of cardiovascular (CV) death…

HALO

The Amulet™ device will be evaluated for safety and efficacy by demonstrating its performance is non-inferior to the commercially available WATCHMAN® left atrial appendage closure…

Amulet™ (AMPLATZER™ Amulet™ LAA Occluder Trial (Amulet IDE))

The Amulet™ device will be evaluated for safety and efficacy by demonstrating its performance is non-inferior to the commercially available WATCHMAN® left atrial appendage closure…

CTD-PAH SWITCH (Crossover Study from Macitentan or Bosentan Over to Ambrisentan (Letairis))

This study is being conducted to learn more about the safety & effects of switching from bosentan (Tracleer) or macitentan (Opsumit) to ambrisentan (Letairis) over…

SPHERE (Uptravi® (SelixiPag): The Users Drug Registry)

This registry is being conducted in order to further outline the clinical characteristics, outcomes and dosing/titration regiments of patients treated with Uptravi in routine clinical…

WISE LE Study (Evaluation of WIRION™ EPS in Lower Extremities Arteries)

The purpose of this study is to demonstrate the safety & performance of the WIRION™ EPS in subjects undergoing lower extremity atherectomy for the treatment…

Reveal LINQ™ Heart Failure (LINQ HF)

The primary objective of this registry is to characterize Reveal LINQ™ derived data from patients with heart failure by assessing the relationship between changes in…