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Bladder Cancer and the effects of Intravesical Therapy

This randomized phase III trial studies Tokyo-172 strain bacillus Calmette-Guerin (BCG) solution with or without a vaccination using Tokyo-172 strain BCG to see how well…

COMET - Communication and Education in Tumor Profiling

This research trial studies how well pre-test genetic education and remote genetic counseling works in communicating tumor profiling results to patients with advanced cancer. Web-based…

Breast Cancer and the effects of Cisplatin With or Without ABT-888 (Veliparib)

This randomized phase II trial studies how well cisplatin works with or without veliparib in treating patients with stage IV triple-negative breast cancer and/or breast…

Selected Hyaluronan High Solid Tumors and the effects of PEGylated Recombinant Human Hyaluronidase

This is a phase 1b study evaluating a combination of PEGPH20 and pembrolizumab for subjects with relapsed/refractory advanced or metastatic Non Small Cell Lung Cancer…

DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

This clinical trial studies nivolumab and ipilimumab in treating patients with rare tumors. Monoclonal antibodies, such as nivolumab and ipilimumab, may interfere with the ability…

Radical Prostatectomy and the effects of Adjuvant Radiotherapy With or Without Adjuvant Docetaxel

This randomized phase II/III trial studies docetaxel, antiandrogen therapy, and radiation therapy to see how well it works compared with antiandrogen therapy and radiation therapy…

Breast Cancer and the effects of Weight Loss in Overweight and Obese Women

This study aims to test whether overweight or obese women who take part in a weight loss program after being diagnosed with breast cancer have…

Breast Cancer and a Comparison of Abbreviated Breast MRI and Digital Breast Tomosynthesis

The purpose of this study is to compare any good and bad effects of using chemotherapy compared to chemotherapy and radiation prior to surgery. This…

Pancreas Cancer and the effects of Chemotherapy vs. Chemotherapy Plus Hypofractionated Radiation

The purpose of this study is to compare any good and bad effects of using chemotherapy compared to chemotherapy and radiation prior to surgery. This…

Ovarian Cancer and the effects of Mirvetuximab Soravtansine (IMGN853)

This is a Phase 3, open label, randomized study designed to compare the safety and efficacy of IMGN853 to that of selected single-agent chemotherapy (Investigator's…