5 results for "Obstetrics and Gynecology"

Preterm Preeclampsia and the effects of Recombinant Human Antithrombin (Atryn)

The purpose of this study is to evaluate the safety and effectiveness of ATryn in subjects with preterm preeclampsia. This study involves research to assess if ATryn can:

  • increase the time the baby stays in the womb
  • decrease problems the mother may experience
  • improve the health and well-being of the baby

Preterm Labor and the effect of the Cervilenze Device

Currently, it is difficult to predict which pregnant women with symptoms of preterm (early) labor will actually experience preterm delivery of the baby. Length of the cervix (the opening to the uterus or womb) in pregnant women has been shown to be one of the risk factors associated with delivering a baby preterm. CerviLenz is a simple, single use device approved by the FDA to measure cervical length. The purpose of the study is to see how well the Cervilenz measurement of cervical length correlates with preterm delivery.

Premenopausal Uterine Fibroids and the effects of Elagolix with Estradiol/Norethindrone Acetate

This study assesses the safety and efficacy of Elagolix 300 mg BID in combination with E2/NETA (estradiol 1.0 mg/norethindrone acetate 0.5 mg QD) compared to placebo in reducing heavy menstrual bleeding associated with uterine fibroids in premenopausal women.

Premenopausal Women with Uterine Fibroids and the effects of Elagolix

This study evaluates the long-term efficacy and safety of Elagolix administered alone and in combination with add-back therapy (estradiol/norethindrone acetate or E2/NETA) to reduce heavy menstrual bleeding (HMB) associated with uterine fibroids.

Endometriosis-Associated Pain and the effects of Elagolix with Estradiol/Norethindron Acetate

This study evaluates the safety and efficacy of Elagolix in combination with concomitant hormonal add-back therapy (E2/NETA) in the management of endometriosis-associated pain (EAP) in premenopausal women.